Gut & digestive health

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Extensive research has been undertaken investigating the effects of fucoidans on gut and digestive health.

The research summary below is provided for scientific and educational purposes only. 

Gut & digestive health

A rapidly expanding body of published research demonstrates the potential of fucoidans to support gut and digestive health (Yang, 2021). Studies investigating the beneficial effects of fucoidans in the gastrointestinal tract include the balancing of gut microbiota (Liu, 2018) through to significant reductions in gut inflammation (Lean, 2015).

Research has shown that fucoidans can:

Fucoidans produced by Marinova

Research has demonstrated that fucoidans can assist in balancing the composition of gut flora. High purity fucoidans produced by Marinova have been shown to inhibit the adhesion of the bacterium H. pylori to gastric epithelial cells (Chua, 2015). H. pylori is widely recognised as a common cause of gastric ulcers.

In mouse models, Marinova’s fucoidans have significantly reduced the clinical symptoms, pathology and cytokine elevations of acute colitis (Lean, 2015), and inhibited inflammation and inflammatory cell death in alcohol induced gastric ulcers (Selim, 2023). In a clinical study involving professional athletes, high purity fucoidan extracted from Fucus vesiculosus and Undaria pinnatifida promoted the secretion of anti-microbial peptides and contributed to the regulation of mucosal inflammation (Cox, 2020).

Marinova’s high purity fucoidan shows promise as a preventative for several gastrointestinal disorders, including cancers closely associated with chronic gastrointestinal inflammation. Fucoidan extracted from Undaria pinnatifida has been shown to induce DNA damage in human colon cancer cells, whilst causing no damage to healthy cells (Corban, 2019).